Motif ID: FOX{C1,C2}.p2

Z-value: 0.403


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXC2chr16_+_866008560.383.5e-01Click!
FOXC1chr6_+_16106800.049.2e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_189839132 0.488 COL3A1
collagen, type III, alpha 1
chr2_+_189839078 0.476 NM_000090
 COL3A1
collagen, type III, alpha 1
chr2_+_189839113 0.396 COL3A1
collagen, type III, alpha 1
chr2_-_158300517 0.358 NM_004288
 CYTIP
cytohesin 1 interacting protein
chr3_+_45927995 0.324 NM_006641
NM_031200
 CCR9

chemokine (C-C motif) receptor 9

chr6_+_47624222 0.254 NM_153839
 GPR111
G protein-coupled receptor 111
chr22_+_31003069 0.247 NM_000355
NM_001184726
 TCN2

transcobalamin II

chr3_-_149095413 0.226 TM4SF1
transmembrane 4 L six family member 1
chr3_-_149095333 0.215 TM4SF1
transmembrane 4 L six family member 1
chr14_+_29236882 0.212 FOXG1
forkhead box G1
chr1_+_163038934 0.208 NM_001113381
 RGS4
regulator of G-protein signaling 4
chr2_-_188419049 0.197 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_33359607 0.176 NM_000627
NM_001166264
NM_001166265
NM_001166266
 LTBP1



latent transforming growth factor beta binding protein 1



chr3_-_149095458 0.167 TM4SF1
transmembrane 4 L six family member 1
chr2_-_216300444 0.155 FN1
fibronectin 1
chr11_-_2156721 0.154 IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_+_51026742 0.147 NM_015915
NM_181598
 ATL1

atlastin GTPase 1

chr17_-_10741398 0.145 NM_001101387
 PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr11_-_59633942 0.132 NM_001062
 TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chrX_+_70521627 0.124 NM_012278
 ITGB1BP2
integrin beta 1 binding protein (melusin) 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.86 4.10e-02 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.03 1.72e-03 GO:0005578 proteinaceous extracellular matrix
2.69 6.70e-03 GO:0031012 extracellular matrix
2.10 3.97e-04 GO:0044421 extracellular region part
1.74 3.03e-04 GO:0005576 extracellular region
1.35 4.71e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
22.05 5.74e-03 GO:0016175 superoxide-generating NADPH oxidase activity
7.72 9.70e-03 GO:0003823 antigen binding